PML Bodies
These are timelapse movies of PML bodies (small foci). The cells are also stained for DNA and/or splicing factor compartments. Experiments were performed in the Michael J Hendzel Laboratory in the Department of Oncology at the University of Alberta.
PML Movie 1: SK-N-SH transfected with PML. A field of SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 1: SK-N-SH transfected with PML. A field of SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 2: A subregion of the cells in Movie 1.
PML Movie 2: A subregion of the cells in Movie 1.
PML Movie 3: A subregion of the cells in Movie 1.
PML Movie 3: A subregion of the cells in Movie 1.
PML Movie 4: SK-N-SH transfected with PML. A field of SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 4: SK-N-SH transfected with PML. A field of SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 5: SK-N-SH transfected with PML. A field of SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 5: SK-N-SH transfected with PML. A field of SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 6: A subregion of the cells in Movie 1
PML Movie 6: A subregion of the cells in Movie 1
PML Movie 7: A subregion of the cells in Movie 1
PML Movie 7: A subregion of the cells in Movie 1
PML Movie 8: A subregion of the cells in Movie 1.
PML Movie 8: A subregion of the cells in Movie 1.
PML Movie 9:SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 9:SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 10: SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 10: SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 11: SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 11: SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 12: SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 12: SK-N-SH transfected with PML. An SK-N-SH human neuroblastoma cells transfected with PML-DsRed (green) and counterstained with Hoechst to visualize the chromatin (red).
PML Movie 13: MCF-7 transfected with PML. MCF-7 breast cancer cells transfected with PML-DsRed (red) and counterstained with Hoechst to visualize the chromatin (green).
PML Movie 13: MCF-7 transfected with PML. MCF-7 breast cancer cells transfected with PML-DsRed (red) and counterstained with Hoechst to visualize the chromatin (green).
PML Movie 14: A mouse fibroblast cell transfected with PML Dsred (red), ASF-GFP (splicing factor, green) and Hoechst (DNA, blue).
PML Movie 14: A mouse fibroblast cell transfected with PML Dsred (red), ASF-GFP (splicing factor, green) and Hoechst (DNA, blue).
PML Movie 15: A mouse fibroblast cell transfected with PML Dsred (red), ASF-GFP (splicing factor, green) and Hoechst (DNA, blue).
PML Movie 15: A mouse fibroblast cell transfected with PML Dsred (red), ASF-GFP (splicing factor, green) and Hoechst (DNA, blue).
PML Movie 16: A high magnification of a subregion of a mouse fibroblast cell transfected with PML Dsred (red), ASF-GFP (splicing factor, green) and Hoechst (DNA, blue).
PML Movie 16: A high magnification of a subregion of a mouse fibroblast cell transfected with PML Dsred (red), ASF-GFP (splicing factor, green) and Hoechst (DNA, blue).
PML Movie 17: SK-N-SH cells transfected with PML-DsRed (red) and then stained with Mitotracker Red (blue) and Hoechst (green).
PML Movie 17: SK-N-SH cells transfected with PML-DsRed (red) and then stained with Mitotracker Red (blue) and Hoechst (green).
PML Movie 18: A mouse fibroblast cell transfected with PML Dsred (blue, bottom left panel), ASF-GFP (green, bottom right panel) and stained with Hoechst (red, top right panel)
PML Movie 18: A mouse fibroblast cell transfected with PML Dsred (blue, bottom left panel), ASF-GFP (green, bottom right panel) and stained with Hoechst (red, top right panel)